Composition
- Each Dry Syrup Contains:
- Amoxycillin Trihydrate 1P
200 mg
- Potassium Clavulanate Diluated IP
28.5 mg
Packing
- 30 ml(240)
(With Carton)
MRP
- 65
Overview
Dry syrups are the mixtures that require the addition of water at the time of dispensing inadequate chemical stability of drug in aqueous vehicle to avoid the physical stability problem.
Amoxicillin
It is a semi synthetic penicillin with a broad spectrum bactericidal activity, and has good oral absorption.It acts through the inhibition of biosynthesis of cell wall.
Potassium Clavunate
It act as a inhibitor of Β-lactamases of Gram +ve and Gram -ve pathogenic bacteria.
Has a protective effect on Amoxicillin Clavulanic acid when combined with Amoxicillin extends the antibacterial spectrum of Amoxicillin to include organisms resistant to Amoxicillin and other beta-lactam antibiotics, It has been demonstrated by recent studies that Amoxycillin and potassium clavunate shows significantly better symptoms relief with the modest improvement of Upper and lower respiratory tract infections.
Indications
Amoxicillin and Potassium clavunate is used in the treatment of a number of infections including:
- Upper and lower respiratory tract infection.
- Otitis Media (inflammation of the middle ear).
- Acute Sinusitis.
- Acute exacerbation of chronic bronchitis.
- Pneumonia.
- Urinary tract infection.
Contraindications
Amoxicillin and potassium clavunate is contraindicated in patients with a history of allergic reactions to any penicillin. It is also contraindicated in patients with a previous history of cholestatic jaundice.
Side Effects
Side effects of Amoxicillin and Potassium clavunate is generally minor and well tolerated:
Diarrhea/loose stools
Nausea
Vomiting
Headache.
Pharmacology
Mechanism of Action
- Penicillin-like antibiotic Amoxicillin works by stopping the growth of bacteria.
- Potassium clavunate works by preventing bacteria from destroying amoxicillin.