Overview

Ifcobal-Vit capsules contain vitamins and vitamin like-antioxidants. The B group vitamins play pivotal roles and have a great impact on neurological health. These B group vitamins have specific effects on brain cell functions and their deficiency leads to different neurological and psychological problems. Mecobalamin is an essential vitamin for the proper functioning and development of the brain and the nerve cells.

Benefits:

• Peripheral and diabetic neuropathy
• Anemia
• Memory function
• Energy production
• Normal functioning of CNS and muscles
• Nerve degeneration.

About Composition

Mecobalamin:

Vitamin B12 or mecobalamin is an essential vitamin for the proper functioning and development of the brain and the nerve cells. It plays an important role in the maintenance of the sheaths that cover and protect the nerves of the central and the peripheral nervous system, ensuring proper and faster nerve-impulse transmission. It is involved in having a healthy nervous system, and plays a vital role in the metabolism of healthy fats essential for maintenance of the important covering that surrounds nerves known as myelin sheath.
Absorption:
Absorbed after oral, sublingual, injection
Excretion:
Excretion via urine

Alpha-lipoic acid:

Alpha-lipoic acid and its reduced metabolite, Dihydrolipoic acid (DHLA), form a redox couple and may scavenge a wide range of reactive oxygen species. Alpha-lipoic acid has been found to decrease urinary isoprostanes, O-LDL and plasma protein carbonyls, markers of oxidative stress. Further, alpha-lipoic acid and its redox couple DHLA have been found to have antioxidant activity in aqueous, as well as in lipophilic regions, and in extra cellular and intracellular environments. Alpha-lipoic acid participates in the recycling of other important biologic antioxidants, such as vitamins E and C, Ubiquinone and glutathione. Both alpha-lipoic acid and DHLA can scavenge hydroxyl radicals, the nitric oxide radical, peroxynitrite, hydrogen peroxide and hypochlorite. Alpha-lipoic acid may scavenge singlet oxygen, and DHLA may scavenge super oxide and peroxyl reactive oxygen species.
Absorption:
Alpha-lipoic acid is absorbed from the small intestine. The natural R-entantiomer is more readily absorbed than the L-entantiomer and is the more active form.
Distribution:
It is distributed to the liver via the portal circulation and to various tissues in the body via the systemic circulation. . Alpha-lipoic acid readily crosses the blood-brain barrier. It is found, after its distribution to the various body tissues, intracellularly, intramitochondrialy and extracellularly.
Metabolism:
Alpha-lipoic acid is metabolized to its reduced form, dihydrolipoic acid (DHLA), by mitochondrial lipoamide dehydrogenase enzyme.

Vitamin B1:
Vitamin B 1 is an essential nutrient, which helps to produce energy from food, contributes to metabolism of glucose and enables proper functioning of the nerves, brain, muscles and heart. Thiamine is a water-soluble vitamin that participates in carbohydrate metabolism. Deficiency of thiamine causes beriberi, characterized by painful peripheral neuropathy and cardiomyopathy. It acts as an activating molecule (cofactor, coenzyme) for the enzymes involved in the breakdown of carbohydrates and proteins and thus enables the release of energy from them and especially important for proper functioning of the nerves, brain, muscles and heart. Thiamine is also involved in the production of gastric acid, neurotransmitters GABA and acetylcholine, maintaining the myelin nerve sheaths and in breakdown of alcohol. Thiamine deficiency may also be involved in the etiology of diabetic neuropathy by preventing the glycation of nerve fibers as well as apoptosis of endothelial cells. Thiamine and pyridoxine were helpful in improving the pain experienced in diabetic peripheral neuropathy as well as improving signs of neuropathy.

Vitamin B6:
Vitamin B6, or pyridoxine, is a vitamin that has many important functions in the body. One of its roles is to help the nervous system work well. The nervous system is what is affected by peripheral neuropathy (PN). Some cases of PN have been linked to vitamin B6 deficiency. It is involved in many areas of your metabolism, from the formation of hemoglobin that carries oxygen in your blood, to the working of your genes, to the release of stored-up glucose in your muscles, and many other important actions including the formation of the biologic chemicals that nerves use to "talk to one another." And like vitamin B12 it is also involved in the formation of the covering for nerves - the myelin sheath, this is one way in which it is directly supports nerve health. Vitamin B6 plays an important role in the body. It is needed to maintain the health of nerves, skin, and red blood cells. Pyridoxine has been used to cure a certain nerve disorder (peripheral neuropathy) caused by certain medications (such as isoniazid).

Folic Acid:
It is essential for methylation, necessary for healthy neurological support. Folic acid is crucial for proper brain function and plays an important role in mental and emotional health. It aids in the production of DNA and RNA, the body’s genetic material, and is especially important when cells and tissues are growing rapidly.

Contraindications:

Hypersensitivity to any ingredient of the composition. Anaphylactic reaction and other sensitivity reactions.

Side Effects

The product is possible safe for most adults. There is no disadvantage associated with the product if taken under the recommended usage. However, some are: headache, nausea, vomiting, and upset stomach.

Pregnant & Lactating:

Store in a cool, dry & dark place. Protected from direct sunlight.