Composition
- Each Soap Contains:
- Permithrin BP
1% w/w
Packing
- 1X75 gm
MRP
- 85
Overview
Permithrin BP 1% W/W soap is an effective medication used to treat infestation of head lice, ticks, fleas and mites on the scalp and the skin. It is also used to treat scabies in adults and children and shows its effects by paralyzing and killing lice and their eggs (nits).
Indications
- Scabies: It is used to treat a highly contagious infection caused by mites marked by intense itching in the affected area.
- Lice manifestation: It is used for the treatment of lice present on the scalp, pubic area, and other parts of the skin.
About Composition
Permethrin is a pyrethroid insecticide used in the treatment of lice infestations and scabies, a condition caused by mites that infest and irritate your skin. Permethrin works by paralyzing and killing the mites and their eggs.
Pharmacology
Pharmacodynamics:
Permethrin, belonging to pyrethroid family, is active against a broad range of pests including lice, ticks, fleas, mites, and other arthropods.
Mechanism of Action:
Permethrin acts on the nerve cell membrane to disrupt the sodium channel current that regulates the polarization of the membrane. Delayed repolarization and subsequent paralysis and death of the parasites are the consequences of this disruption. Permethrin exhibits residual ovicidal activity after rinsing.
Side Effects
Less serious side effects may include:
- Itching
- Redness
- Swelling
- Rash
- numbness or tingling of the skin
- Mild burning or stinging sensation
- Scabies symptoms may temporarily worsen after treatment
Warnings & Precautions
- External use only
- Use permethrin with caution in patients with hypersensitivity
- Avoid contact with eyes
- Increase in symptoms: Use of this medicine may increase itching, swelling, and redness temporarily.
- Pregnancy: It is safe for use by pregnant women but should be used during pregnancy only if clearly needed.
- Breast-feeding: It should be used by women who are breastfeeding only when necessary. It is advised to discontinue breastfeeding when it is applied onto the body.